教育工作经历

1988.9 –1993.7：中国科学技术大学近代化学系，本科
1998.9 –2001.3：福州大学化学系，硕士
2001.10 –2005.9：加拿大舍布鲁克大学核药物和辐射生物系，博士
2005.10 –2007.10：加拿大舍布鲁克大学化学系，博士后研究员
2007.10 –2008.12：加拿大舍布鲁克大学核药物和辐射生物系，助理研究员
2009.1 –至今：福州大学化学学院/国家环境光催化工程技术研究中心  

教学简介

研究生及博士生课程：《现代催化研究方法》、《辐射化学》、《辐射生物化学》
本科生课程：《物理化学》、《辐射科学与现代人类》（校选课）、《教授学科导论讲座》 

科研简介

2009年，根据“福建省高等学校高层次创造性人才计划”引进为“闽江学者”特聘教授，在光催化研究所教育部优秀创新团队的平台上，组建一个国际领先水平的辐射生物化学和生物光催化的基础研究实验室，承担低能电子与生物分子的作用机理、癌症的放射治疗、光催化技术在光动力学治疗和生物化学领域的应用等项目的研究。
长期从事超高真空表面及结构、辐射生物、光催化在医学和生物领域的基础与应用研究。尤其专业于低能电子和辐射生物化学等领域，擅长运用色谱、质谱等化学分析手段。近几年来，主要开展低能电子对DNA损伤和生物光催化的研究。作为项目主要研究人员参与并完成了多项加拿大卫生研究院和癌症研究院等资助项目。在低能电子导致的DNA及其重要成分损伤过程、低能电子的辐射敏化机理以及化疗和放射治疗联合疗法的研究等方面都取得了突出的成果，并在《J. Am. Chem. Soc.》、《Phys. Rev. lett.》、《J. Chem. Phys.》等国际重要学术刊物上发表。
我们课题组长期与加拿大舍布鲁克大学医学院核药物与辐射生物学系合作，联合培养博士生，并派遣硕士生、博士生开展学术交流与合作，特别优秀者可采用联合培养的方式在舍布鲁克大学医学院开展博士课题，也可直接申请加拿大博士学位。欢迎有志从事科研工作的硕士生、博士生、博士后报考我们课题组。  

科研项目

主持的科研项目
1. 国家自然科学基金项目：癌症化放联合治疗中低能电子对DNA多重损伤的机制研究，2017-2020
2. 国家自然科学基金项目：癌症治疗中金纳米粒子的辐射敏化机理研究，2010-2012
3. 闽江学者科研启动项目：低能电子与生物分子的作用机理研究，2009-2011 

代表性论文

1. 5 Wenzhuang Chen, Shiliang Chen, Yanfang Dong, Pierre Cloutier, Yi Zheng,* Léon Sanche, Absolute Cross Sections of DNA strand break and crosslink induced by Low Energy Electron, Phys. Chem. Chem. Phys. 18, 32762-32771 (2016).

2. Jiawen Liu, Xiaobin Yao, Pierre Cloutier, Yi Zheng,* Leon Sanche, DNA strand breaks induced by 0-1.5 eV photoelectrons under atmospheric pressure, J. Phys. Chem. C 120, 487-495 (2016).

3. Xiaobin Yao, Chuanna Huang, Xiaoping Chen, Yi Zheng,* Leon Sanche, Chemical radiosensitivity of DNA induced by gold nanoparticles, J. Biomed. Nanotechnol. 11(3), 478-485 (2015).

4. Qianhong Bao, Yunfeng Chen, Yi Zheng,* Léon Sanche, Cisplatin radiosensitization of DNA irradiated with 2-20 eV electrons: role of transient anions, J. Phys. Chem. C 118, 15516 (2014).

5. Xinglan Luo, Yi Zheng,* Léon Sanche, DNA strand breaks and crosslinks induced by transient anions in the electron-energy range 2-20 eV, J. Chem. Phys. 140, 155101 (2014).

6.Fangxing Xiao, Xinglan Luo, Xianzhi Fu, Yi Zheng*, Cleavage enhancement of specific chemical bonds in DNA by Cisplatin Radiosensitization, J. Phys. Chem. B 117, 4893-4900 (2013).

7. Yi Zheng, Léon Sanche, Low energy electrons in nanoscale radiation physics: relationship to radiosensitization and chemoradiation therapy, Rev. Nanoscience & Nanotechnology 2,1-28(2013).

8. Chuanna Huang, Qianhong Bao, Darel Hunting, Yi Zheng*, Léon Sanche, Conformation-dependent DNA damage induced by gold nanoparticles, J. Biomed. Nanotechnol. 9, 856-862 (2013).

9. Fangxing Xiao, Xiaobin Yao, Qianhong Bao, Danzhen Li, Yi Zheng*, Sensitive marker of the cisplatin-DNA interaction: X-ray photoelectron spectroscopy of Cl, Bioinorganic Chem. Appli. 649640 (2012).

10. A facile and green self-assembly preparation of gold nanoparticles/ZnO nanocomposite for photocatalytic and photoelectrochemical applications
J. Mater. Chem. 22, 2868 (2012).

11. On the role of low-energy electrons in the radiosensitization of DNA by gold nanoparticles
Nanotechnology, 22, 465101 (2011).

12. Influence of organic ions on DNA damage induced by 1 eV to 60 keV electrons
J. Chem. Phys., 133, 155102 (2010).

13. Protection by organic ions against DNA damage induced by low energy electrons
J. Chem. Phys., 132, 045102 (2010).

14. Gold nanoparticles enhance DNA damage induced by anti-cancer drugs and radiation
Radiation Research, 172, 114-119 (2009).

15. Radiosensitization by gold nanoparticles: Comparison of DNA damage induced by low and high-energy electrons
J. Biomedical Nanotechnology, 4(4), 469-473 (2008).

16. Role of secondary low-energy electrons in concomitant chemoradiation therapy of cancer
Phys. Rev. Lett., 100, 198101-4 (2008).

17. Low Energy Electron Induced DNA Damage: Effects of Terminal Phosphate and Base Moieties on the Distribution of Damage
J. Am. Chem. Soc., 130, 5612-5613 (2008).

18. Radiosensitization of DNA by gold nanoparticles irradiated with high-energy electrons
Radiation Research, 169, 19-27 (2008).

19. DNA damage induced by low-energy electrons: electron transfer and diffraction
Phys. Rev. Lett., 96, 208101 (2006).

20. Phosphodiester and N-glycosidic bond cleavage in DNA induced by 4-15 eV electrons
J. Chem. Phys., 124, 064710 (2006).

21. Chemical basis of DNA sugar-phosphate cleavage induced by low-energy electrons
J. Am. Chem. Soc., 127, 16592-16598 (2005).

22. Irradiator to Study damage induced to large nonvolatile molecules by Low-energy Electrons
Review of Scientific Instruments, 75, 4534 (2004).

23. Glycosidic N-bond cleavage of thymidine induced by low energy electrons
J. Am. Chem. Soc., 126, 1002 (2004).